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Search Results for " d-amino-acid oxidase "

Targets Recommended: Others

8

抑制剂 & 化合物

4

天然产物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T7476	AS057278 3-Methylpyrazole-5-carboxylic acid,5-甲基-1H-吡唑-3-羧酸	Others	Others
	AS057278 (3-Methylpyrazole-5-carboxylic acid) 是一种 D-氨基酸氧化酶 (DAAO) 抑制剂。
T76170	D-Amino acid oxidase
	D-Amino acid oxidase 是一种酶，主要负责在动物体内代谢外源性 D-氨基酸以进行解毒，并能够调节大脑中D-丝氨酸的水平。
T38863	Luvadaxistat TAK-831,Luvadaxistat
	TAK-831 is a potent and highly selective inhibitor of D-amino acid oxidase (DAAO), offering great potential for utilization in schizophrenia research.
T5206	DAAO inhibitor-1	Others	Others
	DAAO inhibitor-1是 D-氨基酸氧化酶抑制剂(IC50:0.12 μM)。
T8124	Sodium benzoate Benzoic acid sodium salt,苯甲酸钠	Others	Others
	Sodium benzoate (Benzoic acid sodium salt) 是一种 D-氨基酸氧化酶抑制剂。它是一种食品防腐剂。
T28964	Thiolactomycin
	Thiolactomycin is a novel reversible dual inhibitor of D-amino acid oxidase (DAO) and D-Aspartate oxidase (DDO).
T78231	DAO-IN-1	Others	Others
	DAO-IN-1是高效的D-氨基酸氧化酶（DAO）抑制剂，其IC50值为269 nM。DAO负责d-丝氨酸的代谢，而d-丝氨酸是NMDA受体的共激动剂。
T37605	D-DOPA
	D-DOPA is an enantiomer of the dopamine precursor L-DOPA . It can be converted to L-DOPAviasequential oxidation and transamination, which are mediated by D-amino acid oxidase (DAAO) and DOPA transaminase, respectively, in rat kidney homogenates.1It reduces the number of dopaminergic neurons in primary rat embryonic mesencephalic cultures in a concentration-dependent manner.2Intraventricular administration of D-DOPA (200 μg/animal) increases striatal dopamine levels in rats.3D-DOPA (20 mg/kg, i.p...

化合物

Cat.No: T7476

Synonym: 3-Methylpyrazole-5-carboxylic acid,5-甲基-1H-吡唑-3-羧酸

Target: Others

D-Amino acid oxidase

Cat.No: T76170

Cat.No: T38863

Synonym: TAK-831,Luvadaxistat

DAAO inhibitor-1

Cat.No: T5206

Target: Others

Sodium benzoate

Cat.No: T8124

Synonym: Benzoic acid sodium salt,苯甲酸钠

Target: Others

Cat.No: T28964

Cat.No: T78231

Target: Others

Cat.No: T37605

Cat. No.	Product Name	Target	Signaling Pathways
T10933	D-Cysteine	Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology
	D-Cysteine 是一种大肠杆菌生长的有力抑制剂，是半胱氨酸的 D 型异构体。它由 D-氨基酸氧化酶介导产生 H2S，是一种对抗小脑共济失调的神经保护剂。 D-半胱氨酸可以抑制由变形链球菌和链球菌血红蛋白形成的两种生物膜的生长和致龋性。
T19302	D(-)-2-Aminobutyric acid	Endogenous Metabolite	Metabolism
	D(-)-2-Aminobutyric acid 是一种 D-氨基酸氧化酶的底物。
T4716	Pyrrole-2-carboxylic acid 吡咯-2-羧酸,2-Pyrrolecarboxylic acid,Minaline	Endogenous Metabolite	Metabolism
	Pyrrole-2-carboxylic acid (Minaline) 是一种天然生物碱类，从海洋细菌Pelomonas puraquaesp. Nov 中分离得到。
T10938	D-Kynurenine D-尿嘧啶,(R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103	GPR; AhR; Endogenous Metabolite	Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Metabolism
	D-Kynurenine (ZINC901103) 是 D-色氨酸的代谢物和 GPR109B 的激动剂。 D-Kynurenine 激活 AhR 并促进上皮细胞向间充质的转化。 D-Kynurenine 在 D-氨基酸氧化酶的荧光分析中用作底物。

天然产物

Cat.No: T10933

Target: Endogenous Metabolite, Antibacterial

D(-)-2-Aminobutyric acid

Cat.No: T19302

Target: Endogenous Metabolite

Pyrrole-2-carboxylic acid

Cat.No: T4716

Synonym: 吡咯-2-羧酸,2-Pyrrolecarboxylic acid,Minaline

Target: Endogenous Metabolite

Cat.No: T10938

Synonym: D-尿嘧啶,(R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103

Target: GPR, AhR, Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00853	DAO Protein, Human, Recombinant (His) D-Amino-Acid Oxidase,	Human	E. coli
	D-Amino-Acid Oxidase (DAO) belongs to the DAMOX/DASOX family. DAO is a peroxisomal enzyme which founctions as a homodimer to oxidizes D-amino acids to the corresponding imino acids, producing ammonia and hydrogen peroxide. D-amino-acid oxidase regulates the level of the neuromodulator D-serine in the brain, has a high activity towards D-DOPA and contributes to dopamine synthesis. D-amino-acid oxidase could act as a detoxifying agent which removes D-amino acids accumulated during aging. It also a...
TMPH-03276	DAO Protein, Rat, Recombinant (His & Myc) D-amino-acid oxidase,	Rat	E. coli
	Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. DAO Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression sy...
TMPH-02621	DAO Protein, Mouse, Recombinant (His) DAMOX,Dao1,DAO,DAAO,...	Mouse	E. coli
	Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. DAO Protein, Mouse, Recombinant (His) is expressed in E. coli expression system...

重组蛋白

DAO Protein, Human, Recombinant (His)

Cat.No: TMPJ-00853

Species: Human

Expression System: E. coli

DAO Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03276

Species: Rat

Expression System: E. coli

DAO Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02621

Species: Mouse

Expression System: E. coli

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